This is the Telok Ayer Performing Arts Centre at 182 Cecil Street.
It was previously the Telok Ayer Primary School.
In 1985, the primary school was converted to be a performating arts centre. Also, known as TAPAC, it houses arts groups of different cultural traditions and art disciplines.
Visit http://kamaldollah.wordpress.com/2007/05/21/singapore-city-mural/ to read about the artists behind this wall.